Application of Support Vector Machine in Medical Diagnosis Anto Satriyo Nugroho School of Life System Science & Technology, Chukyo University Japan Email : nugroho@life.chukyo-u.ac.jp URL : http://asnugroho.net Support Vector Machine (SVM) received increasing attention, and it has been successfully applied in various fields. SVM in principle is a linear machine which is trained to find the optimal discriminating hyperplane in the feature space by maximizing the margin between the classes. The training phase of SVM is conducted based on structural risk minimization, different from neural networks that follow the empirical risk minimization. This is the reason why SVM are often reported to achieve better generalization than conventional pattern recognition method such as neural networks. Computer Aided Diagnosis, on the other hand, requires a method with high accuracy, while the information is often noisy, high dimensional setting, small sample and incomplete. To deal with problem with such characteristics, we develop a computer aided diagnosis system using Support Vector Machine that is combined with individual merit base feature selection. The experimental results showed that SVM achieved good results, and robust to the existence of irrelevant features.